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Therefore, we do not claim direct causality between an individuals prior B12 test and their hospitalization episode, although a significant correlation exists in large populational level between vitamin B 12 deficiency and hospital admissions for cardiovascular, hematological, neurological, psychological, and gastrointestinal diseases

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7 Environmental factors play a role in this system, with sensory information fed into the central clock through signals from the eye, which are then converted to chemical signals in the SCN and synchronized with the peripheral systems