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A sensitive qualitative HCV RNA assay is necessary at 24 weeks in patients infected with genotype 1 with indication of treatment for 48 weeks, since the probability of sustained virological response (SVR) is extremely low when HCV RNA is still detectable at week 24.30-32 HCV RNA negativity for all genotypes 24 weeks after stopping the treatment indicates a sustained virological response

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doi: 10.1016/j.burns.2004.10.013

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