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Moreover, targeting upstream kinases such as ASK1 or mixed-lineage kinase3 (MLKL3) attenuated JNK activation and liver injury (Xie et al., 2015), highlighting the hierarchical relationship between ASK1 and JNK in APAP hepatotoxicity

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Sciatic nerve pain on the right and left sides of the body Cauda equina syndrome can cause a stabbing, sharp, and/or hot pain that radiates from the bottom of the spine down the backs of the legs

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178 Inducing ferroptosis may be an important therapeutic strategy to reverse drug resistance in GBM with high expression of Nrf2 and ABCC1