how long are you on semaglutide Does It Take for to Work? How Long Does Semaglutide Stay

Doctors say there are several reasons why GLP-1 medications may not work for you, but there are alternative options available

Months 23: Consistent Weight Loss This is when semaglutide weight loss often becomes more noticeable

How Much Weight Loss Does Each Produce

3 Emerging research suggests GLP-1 medications may be particularly effective for menopause weight gain: A 2025 study presented at the Menopause Society meeting found that postmenopausal women on hormone replacement therapy (HRT) lost 19.9 percent of their body weight on tirzepatidesignificantly more than the 15.6 percent loss seen in postmenopausal women not using HT

Topiramate (generic for Topamax) : Topiramate is a medication thats commonly used to treat epilepsy and prevent migraines, but its also sometimes prescribed off-label for weight loss