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While peptide drugs have a wide range of therapeutic applications, their relatively short half-life has been a challenge, attributed to poor metabolic stability and a fluid dynamic radius below the glomerular filtration limit of the kidneys

Additionally, manual scrutiny of reference lists within selected articles was conducted to identify supplementary sources

1 Using data from the global TriNetX health research network, the authors conducted a retrospective study that included a total of 91,408 patients aged 55 or older

Clinical Trial Results and Weight-Loss Data Early results published in the New England Journal of Medicine (2023) showed that participants taking Retatrutide experienced up to 24 % average weight reduction after 48 weeks the strongest data reported for any injectable obesity therapy so far

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