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Eli Lillys GLP-1 offering, tirzepatide, launched shortly after (as Mounjaro for T2D in 2022 and Zepbound for obesity in 2023), demonstrated greater HbA1c reduction and up to a 20% placebo-adjusted weight loss

While this demonstrates tirzepatide's potent glucose-lowering effects, it's important to note that the American Diabetes Association generally recommends an A1C target of less than 7% for many nonpregnant adults with diabetes, with individualized goals based on patient factors