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Cold powder dissolves more slowly and can lead to incomplete dissolution if you rush the process

up to 20-30% of older adults struggle with it due to lower stomach acid

In healthy fasted individuals, it is recognized that peripheral plasmatic active GLP-1 (7-36) NH2 plasmatic levels hover around 5 pM, but within 510 min after an oral glucose load, they start to rise, up to a maximum of less than 10 pM after 4090 min, and slowly descend back to baseline values in 150 min

Patients should be aware that whilst constipation is an expected side effect for some, it is manageable