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PLoS One 8:e59827 Cheng R, Li C, Li C, Wei L, Li L, Zhang Y, Yao Y, Gu X, Cai W, Yang Z, Ma J, Yang X, Gao G (2013) The artemisinin derivative artesunate inhibits corneal neovascularization by inducing ROS-dependent apoptosis in vascular endothelial cells

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In many in vivo disease studies or oxidative stress stimulation models, GPX1 deficiency enhances cell damage, apoptosis, and even leads to cell death

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