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Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome

Treatment with hCiPSCs facilitated a shift towards a healthier composition, evidenced by a reduction in Desulfovibrionaceae and a re-emergence of Lactobacillaceae and Muribaculaceae

When both receptor families are activated at the same time, several experimental datasets suggest that growth hormone output may rise beyond what is seen with either pathway alone, which is compatible with additive or synergistic coupling at the level of pituitary signaling

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