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In humans and mice with sepsis, plasma HS levels peak earlier than Ang-2 levels, indicating a correlation between HS levels and organ damage in sepsis, as well as poor prognosis [48]

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Risk of ERD for SARS-CoV-2 vaccines Safety concerns for SARS-CoV-2 vaccines were initially fuelled by mouse studies that showed enhanced immunopathology, or ERD, in animals vaccinated with SARS-CoV following viral challenge 55,56,57,58

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