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Blood markers may change before nerve symptoms improve, and long-standing neurologic symptoms may take longer to assess

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After the initial 1 min isocratic elution of 90% B, the percentage of Solvent B decreased to 40% at t = 11 min

IBS is a diagnosis of exclusion, meaning doctors rule out other diseases (like inflammatory bowel disease or coeliac disease), and it tends to follow a relapsing-remitting course