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doi: 10.1038/s41574-019-0176-8 22

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Serum levels of resistin were markedly elevated in CKD patients with both advanced and mild to moderate renal impairment ( In summary, it is convincing that elevated renal-related inflammation biomarkers play an important role in possible adverse effects on the kidney

In REDEFINE 1 (NEJM 2025, n=3,417, 68 weeks), cagrilintide monotherapy at 2.4 mg produced 11.8% mean body-weight reduction versus 2.3% with placebo