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It really drives home the point that moving from a stable, lyophilized peptide to a functional solution hinges on picking the right solvent and using the right technique

As summarized in the award announcement, Bjerre Knudsen and DiMarchi overcame significant obstacles in bringing these drugs to patients seeking to lose weight

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Microsomal triglyceride transfer protein (MTTP) expression, essential for VLDL assembly, is also reduced in NAFLD, often in parallel with downregulation of apolipoprotein B (ApoB)both of which are critical for efficient hepatic lipid export