This enzymatic process effectively prevents the transmission of lipid peroxides, thereby inhibiting ferroptosis
CougnouxAYergerJCFellmethMSerra-VinardellJWassifCACawleyNXet alToll-like receptor mediated lysozyme expression in niemann-pick disease, type C1
Adv Pediatr 33:95126 Gretz N, Manz F, Augustin R, Barrat TM, Bender-Gotze C, Brandis M, Bremer HJ, Brodehl J, Broyer M, Bulla M, Callis L, Chantler C, Diekmann L, Dillon MJ, Egli F, Ehrich JH, Endres W, Fanconi A, Feldhoff C, Geisert J, Gekle D, Gescholl-Bauer B, Grote K, Gruttner R, Hagge W, Haycock CB, Hennemann H, Klare B, Leupold D, Lohr H, Michalk D, Oliveira A, Ott F, Pistor K, Rau J, Scharer K, Schindera F, Schmidt H, Schulte-Wissermann H, Verrier-Jones K, Weber HP, Willenbockel U, Wolf H (1983) Survival time in cystinosis
NAPQI The metabolism of acetaminophen (Figure 2) by CYP2E1 forms NAPQI, a reactive metabolite that binds to cysteine residues in cellular proteins and forms acetaminophen protein adducts, referred to as acetaminophen-cysteine complexes (APAP-CYS)
Protection against paraquat treatment, locomotor impairment, shortened lifespan, and increased lipid peroxidation was observed in parkin RNAi flies treated with Persea americana peel extracts 30
