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These findings underscore lipid peroxide accumulation as a hallmark of ferroptosis, and suggest that downregulating ACSL4, LPCAT3, LOXs, or POR can suppress PUFA-PL-OOH formation and effectively inhibit ferroptosis

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Elevated clarithromycin resistance has resulted in a declining eradication rate of the conventional first-line triple therapy (containing clarithromycin) to less than 70% (Liang et al