There is no significant inflammation
By using 1,1-dioctadecyl-3,3,3,3-tetramethylindotricarbocyanine iodide (DiR), a near IR fluorescent and hydrophobic carbocyanine, as a fluorescence tracking agent, whole body imaging demonstrated that COXP micelles delivered DiR to mouse brains about 20 times higher than DiR administered alone [52]
These new agents aim to offer enhanced tolerability and minimize adverse events compared to traditional treatments
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That usually makes each syringe unit contain fewer micrograms