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Author contributions Conceived and designed the experiments: ZY, LL, YZ, and PC
This retrospective study across 12 databases in the Observational Health Data Sciences and Informatics (OHDSI) network over a seven-year period included data on adults with type 2 diabetes on semaglutide, other GLP-1 drugs (dulaglutide, exenatide) or non-GLP-1 drugs (empagliflozin, sitagliptin, glipizide)
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Knee pain, measured using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), improved by up to 4.5 points, representing a 75.8% reduction from baseline
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