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Why does hydroquinone cause rebound hyperpigmentation when you stop using it? Hydroquinone destroys tyrosinase irreversibly by denaturing the enzymes copper active site, which triggers melanocytes to upregulate MITF (microphthalmia-associated transcription factor) the master regulator of melanocyte activity as a compensatory response

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"This information includes how they are manufactured, whether they are sterile, how they work in the body, what side effects they may cause and what substances these products actually contain." The regulator said examples of unapproved peptide products included those containing BPC157, GHKCu, TB500, retatrutide and CJC1295, often supplied in injectable form