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Disruption of Cdk5-associated phosphorylation of residue threonine-161 of the delta-opioid receptor: impaired receptor function and attenuated morphine antinociceptive tolerance

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Concerning the regulation, CT2 seems to respond to progesterone stimuli (Sato et al., 2007)

This limitation can be overcome by sequential imaging or by transposing the CT scanner during acquisition 186

The excessive synthesis of insulin and glucagon in pancreatic islets was probably due to the hyperplasia of pancreatic islets or increased proportions of hormone-secreting endocrine cells, or both