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Notice changes like looser-fitting clothes, increased energy, better mobility, and improved mood

doi: 10.1038/sj.emboj.7600110 236 SarbassovDDAliSMKimDHGuertinDALatekRRErdjument-BromageHet al

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Mild to moderate nausea in days 24 confirms your body is responding to the medication and receptors are activating