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204 Similarly, administration of the PRMT5 inhibitor PJ-68 in a CML mouse model with high expression of PRMT5 LSCs could deplete DVL3, thereby inhibiting Wnt/-catenin signaling and significantly prolonging the survival time of a retroviral BCR-ABL-driven CML mouse model

This stage involves rapid cell division that supplies fresh cells for the upper layers

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established a topical gel using Moringa oleifera extract nanoparticles with biopolymer Zein and findings showed significant spreadability, extrudability, stability, and activity [148]