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Besides the well-established role of glutathione as an antioxidant, it serves other functions in the nervous system, including neutralization of xenobiotics, participation in amino acid transport, regulation of the activity and conformation of proteins, protection against cysteine and glutamate neurotoxicities, and modulation of glutamatergic transmission

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In clinical studies there have been no reported serious side effects, even at high doses

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N-acetylcysteine amide (naca) prevents retinal degeneration by up-regulating reduced glutathione production and reversing lipid peroxidation