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Injection site reactions Redness, swelling, or itching at the injection site

Three of those trials were double-blind, randomized, placebo-controlled trials (along with 16 weeks of dose escalation)

Out of over 17,000 patients on Tirzepatide, 10 reported gastroparesis

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Side effects with Wegovy 7.2 mg The STEP UP trial found that side effects were somewhat more common at the higher dose: 2 GI side effects: 70.8% (7.2 mg) vs 61.2% (2.4 mg) Dysaesthesia (tingling/numbness): 22.9% (7.2 mg) vs 6.0% (2.4 mg) Discontinuation due to side effects remained low at 3.3% The dysaesthesia finding is notable, though 85.7% of cases resolved while continuing treatment