(For men, a waist over 40 inches is of concern
In SURMOUNT-5, a head-to-head trial against semaglutide 2.4mg (Wegovy), tirzepatide produced 47% greater weight loss (20.2% vs 13.7%)

During treatment with Wegovy , patients should contact their healthcare provider if they experience: Severe or persistent nausea, vomiting, or diarrhoea that affects daily functioning or causes dehydration Severe abdominal pain, particularly if accompanied by nausea and vomiting (potential pancreatitis) Symptoms of gallbladder disease (pain in right upper abdomen, fever, jaundice) Signs of allergic reaction including rash, itching, or difficulty breathing Mood changes or depression (report but note no established causal link) Symptoms of hypoglycaemia if taking diabetes medications concurrently Unexplained lumps or swelling in the neck For patients with diabetes: changes in vision that could indicate diabetic retinopathy If considering changes to weight loss treatment , including questions about combining medications or switching therapies, patients must discuss this with their prescribing physician

In January 2023, Dustin Gee went for his annual checkup with his primary care doctor, concerned about the 50 pounds he had gained over the past three years
Frequently asked questions Can I use a regular syringe instead of an insulin syringe for semaglutide