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WT BMmacs stimulated with LPS plus IFN- for 24 hours had decreased oxygen consumption rate (OCR) but increased extracellular acidification rate (ECAR) (Supplemental Figure 11, A and B), whereas WT BMmacs stimulated with IL-4 for 24 hours displayed both increased OCR and increased ECAR (Supplemental Figure 11, C and D)

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Cortisol and growth hormone work slowly over hours to defend against prolonged hypoglycemia, but they play a minimal role in reversing hypoglycemia