The results showed that treatment with Tesofensine led to significant weight reduction compared to the placebo group

Key symptoms of PCOS Common symptoms of PCOS: Infrequent, irregular, prolonged, or missed periods Heavy bleeding during periods Hirsutism (excessive hair growth on the face, chest, and back) Severe acne Male-pattern baldness or thinning of hair Enlarged ovaries containing numerous small fluid-filled sacs (follicles) Difficulty losing weight Accumulation of fat, particularly around the abdomen (pear-shaped obesity) Elevated blood sugar levels Increased risk of type 2 diabetes Darkening of the skin in the neck, groin, and underneath the breasts (acanthosis nigricans) Skin tags Difficulty getting pregnant due to irregular ovulation or anovulation (lack of ovulation) Anxiety and depression Mood swings Women with PCOS are more likely to have health conditions, including diabetes, high blood pressure, high cholesterol, heart disease, obstructive sleep apnea, stroke, and endometrial cancer
now Ozempics label carries that warning as well
As in phase 2, the weight loss in phase 3 is slower
If you experience significant gastrointestinal side effects during dose escalation, your prescriber may delay moving to the next dose level