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For the purpose of this review, GLP-1based therapies are GLP-1 receptor agonists such as exenatide, liraglutide, and others or dipeptidyl peptidase-4 (DPP-4) inhibitors such as sitagliptin, vildagliptin, saxagliptin, alogliptin, and linagliptin (8)

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The findings of the SURMOUNT OSA trial supported this hypothesis, showing a significant improvement in AHI, hypoxic burden and sleep quality with tirzepatide compared to placebo at 52 weeks 38