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180,181 Motor symptoms include progressive weakness and atrophy of proximal lower-limb muscles, leading to difficulty rising from a seated position or climbing stairs, accompanied by muscle fasciculations and hyporeflexia

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These medicines are generally used alongside reduced-calorie nutrition, physical activity and ongoing clinical monitoring

J Nutr (2013) 143:5916.10.3945/jn.112.167593 128 BatterhamRLHeffronHKapoorSChiversJEChandaranaKHerzogHet alCritical role for peptide YY in protein-mediated satiation and body-weight regulation