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For patients who are more sensitive to nausea, I may prescribe anti-nausea medication, says Mir Ali, MD, a bariatric surgeon, bariatric medicine specialist, and the medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in Fountain Valley, California

While initially approved for Type 2 diabetes, its increasingly prescribed off-label for weight loss due to its strong results

A study of more than 600,000 veterans followed for up to three years found that those who started taking a GLP-1 drug for diabetes were about 15% to 20% less likely to misuse substances ranging from alcohol to opioids

A separate study from Mass General Brigham found that women who discontinued GLP-1 medications before or early in pregnancy gained an average of 7.2 pounds more during pregnancy and experienced higher rates of gestational diabetes, hypertensive disorders, and preterm birth

Krenkel O, Tacke F