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Monitoring schedule Healthcare providers who specialize in GLP-1 therapy typically recommend this monitoring cadence: Baseline: Full B12 panel before starting semaglutide 3 months: Repeat serum B12 and MMA 6 months: Full panel reassessment Annually: Once stable, annual monitoring is usually sufficient For high-risk patients (metformin users, vegans, those over 60, post-bariatric surgery), the 3-month check is particularly important

The reason is structural, not personal

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There is also uncertainty over the long-term effects of GLP-1 receptor agonists for weight management in those without diabetes

CMS is launching a program called the Medicare GLP-1 Bridge which gives eligible beneficiaries access to GLP-1 drugs for a $50 monthly copay