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Funding This study was supported by grants from the National Natural Science Foundation of China (82302925, 82272702), Natural Science Foundation of Zhejiang Province (LQ23H160012, LZ23H160001, LTGY23H080005), the project of Science and Technology Plan of Traditional Chinese Medicine of Zhejiang Province (2024ZL1010), Wenzhou Science and Technology Bureau of China (ZY2023021), and in part supported by the Key Discipline of Zhejiang Province in Medical Technology (First Class, Category A)
High stress levels increase cortisol, which can lead to dullness and uneven skin
Urbano et al., 2017)
Bioflavonoids : These plant-based chemicals in citrus fruits and blackcurrants may act as natural antihistamines
Quercetin shows marked anti-inflammatory activity by inhibition of inflammatory signaling pathways such as NF-B, NLRP3 inflammasome, and cyclooxygenase pathway while hyperoside precipitates anti-inflammatory effects by suppression of NFB mediated signaling (Kim et al., 2011)
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