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Why does type 2 diabetes mellitus impair weight reduction in patients with obesity

"Our results indicate that further research into semaglutide's use will need to be further investigated through randomized clinical trials so alternative drugs can be tested as potential treatment for this debilitating illness," Xu said

Rapid fat mobilization during weight loss, and dehydration from reduced appetite, can temporarily affect liver enzymes

This hormone helps regulate appetite, slows gastric emptying, and improves blood sugar levels, reducing calorie intake and weight loss

Importantly, the study does not establish causality, and the researchers do not yet understand why this association exists or why the risk differences were observed between diabetic and overweight groups