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Moreover, FA cytotoxicity can be prevented by supplying the GSH-precursors N-acetyl-L-cysteine (NAC) or GSH-monoethyl ester (GSH-MEE), and it is exacerbated by inactivating cellular GSH synthesis

It is a cofactor for lysyl oxidase, the enzyme that crosslinks new collagen and elastin into mature, stable matrix proteins

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There is ongoing litigation among manufacturers, compounding pharmacies and the FDA on how long compounding pharmacies can dispense the drugs, given that the FDA has announced the resolution of the shortage