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The Drosophila caspase DRONC cleaves following glutamate or aspartate and is regulated by DIAP1, HID, and GRIM

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For GHK-Cu specifically, the logic is sound even without direct evidence: cumulative copper exposure is lower with reduced frequency, and the gene expression changes initiated during loading persist during maintenance

One of these priorities is improving our understanding of the clinical, quality-of-life and cost-effectiveness of self-care for PA patients - including self-administering B 12 injections - which could empower patients to manage their symptoms and reduce NHS costs