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Neonatal opioid withdrawal syndrome, unlike opioid withdrawal syndrome in adults, may be life-threatening if not recognized and treated, and requires management according to protocols developed by neonatology experts

doi: 10.1016/j.isci.2019.03.028 145 ZhangLWangSZhouYWangCZhangX-ZDengH

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4a), further validating the impaired extinction in the PTSD-like model