For instance, cluster 1a in Figure 5A comprises proteins whose transcript levels are higher than those of proteins in cluster 1b
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Rossini, M., Di, Munno O., Valentini, G., Bianchi, G., Biasi, G., Cacace, E., Malesci, D., La, Montagna G., Viapiana, O., and Adami, S
Acta Pharmacol Sin 35(11):14021410 Ramakrishna K et al (2024) Indole-3 carbinol and diindolylmethane mitigated beta-amyloid-induced neurotoxicity and acetylcholinesterase enzyme activity: in silico, in vitro, and network pharmacology study
While these findings dont directly translate to humans, they raise legitimate concerns about reproductive health, endocrine disruption, and metabolic stress with prolonged, high-dose usage
