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This capacity allows them to colonize adhesion sites, including colonic crypts, goblet cells, and intestinal villi, in substantial numbers, thereby physically preventing pathogens from gaining a foothold and establishing infection (163, 192)

The relapse rate after steroid treatment ranges between 33% and 75%

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As to the pi class, GSTP1-1 point mutations in both exon 5 (codon 105) and exon 6 (codon 114) were observed and shown to have an impact on the enzymatic activity 32

Chronic mitochondrial ROS production in HF further drives myocyte apoptosis via ROS-mediated activation of caspases and mPTP opening, fibrosis through ROS-activated TGF- signaling in fibroblasts, and electrical instability due to oxidative damage to ion channels, increasing arrhythmia risk