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Acknowledgements We acknowledge the use of the Iridis5 High-Performance Computing Facility and Flow Cytometry Core Facilities, together with support services at the University of Southampton

It reduced neuronal damage and improved memory, locomotion, and coordination, possibly by influencing gene expression in hippocampal tissues

Slow Rolling: Alternatively, you can roll the vial gently between your palms

Review all medications with the prescriber, follow titration instructions carefully and never increase a dose early because weight loss has slowed

Beyond nausea, slower dose advancement reduces the likelihood of vomiting, constipation, and appetite loss so severe that nutritional intake becomes unsafe