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Compounded GLP-1 (FDA): Compounded semaglutide and tirzepatide are not FDA-approved and have not been evaluated by the FDA for safety, effectiveness, or quality

International research has raised concerns about a disproportionately high risk of suicidal ideation among people with anxiety or depression who take semaglutide

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Simultaneously, semaglutide suppresses inappropriate glucagon secretion from pancreatic alpha cells, further contributing to improved glycemic control

While not having to pass health questions is a definite plus, the flip side of that is their plans are a little more expensive