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So far, trials have not demonstrated gross impairment of growth or bone mineral density, and some data suggest possible bone-protective effects, but pediatric data are limited ( could exacerbate social stigmatization or prompt feelings of shame if weight rebounds after stopping therapy ( Optimizing the real-world implementation of these therapies is another important avenue

Retrieved March 27, 2019

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A study in JAMA demonstrated that participants who stopped semaglutide after short-term use regained a significant portion of lost weight within months