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Romanelli MMC, Vianello E, Malavazos AE, Tacchini L, Schmitz G, Iacobellis G, et al

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The median time to an irAE was 2.8 months (range, 0.3-13.8 months), 6 (33.3%) patients required hospitalization, 11 (61.1%) required systemic steroids, and 13 (72%) patients required a therapy interruption for at least 1 week (10 (77%) of which permanently discontinued treatment)

International Journal of Peptide and Protein Research, 24 (3), 208-217

This study aimed to delve into the individual and combined prophylactic effects of Vitamin C (Vit C) and Coenzyme Q10 (CoQ10) against inflammatory heart injury in a cecal ligation and puncture (CLP) induced polymicrobial sepsis rat model