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Qin and colleagues have shown that melatonin protects the bloodbrain barrier through upregulation of TIMP1 in pericytes and regulation of the NOTCH/NFB pathway (Qin et al., 2019)

Nguyen ST, Otoi T, Namula Z, Widodo OS, Tharasanit T, Chatdarong K, Tanihara F Mitochondrial-Targeted Protective Potential of Elamipretide for the In Vitro Production of Porcine Embryos

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In humans, AA and linoleic acid are the most abundant PUFA that serve as the preferred oxidation site for LOXs using molecular oxygen to form hydroperoxyl radicals at different carbon position of acyl chains