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That effect is well-supported by exercise-dehydration research and is generally small under everyday conditions, but becomes more meaningful in heat, at altitude, after exercise, or during illness

& Cheng, Y

10.1016/j.abb.2019.01.003 Arch

Consequently, a precise understanding of the signals that govern these cell fates is fundamental to developing therapies that can recalibrate the Th17/Treg balance in disease