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When allopurinol is administered along with purine-based chemotherapy drugs such as mercaptopurine (Purinethol) or azathioprine (Imuran, Azasan), reduction of the chemotherapy dosage is required

In a pooled analysis of placebo-controlled trials, increases in serum transaminases to more than three times the ULN occurred in 1.1% of patients taking rosuvastatin versus 0.5% of patients treated with placebo

Too much vitamin A may also lead to liver toxicity and damage the liver

PlexusDx recommends prioritizing proven weight loss mechanisms before adding supplements without established synergistic effects

Large-scale human clinical trials have not yet been completed