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This result suggests that ARA 290 has a complex activity that extends beyond the sensation of pain to include effects on activities of daily living

The low dose of orforglipron yielded average weight loss of about 5.5% (12.1 lbs) and A1C reduction of 1.6%, while the middle dose resulted in 7.8% average weight loss (17.4 lbs) and 1.3% A1C reduction

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