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During the novel object recognition (NOR) tests, gradually deteriorating short-term (1-h) and long-term (24-h) cognitive impairments occurred with the increasing time of ethanol exposure, while earlier and severer recognition memory loss were found in APP/PS1 mice, compared to WT mice (Fig

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Curr Opin Pharmacol

When caspase-8 activity is inhibited, TRAF2 prompts RIPK1 to bind RIPK3 with the formation of a necrosome complex also known as ripoptosome [209]