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In this context, exploring the mechanistic relationship between GLP-1 receptor activation and mitochondrial function in the brain may provide valuable insights into novel therapeutic strategies for AD ( This review highlights estrogens role in the central nervous system, with emphasis on their regulatory functions in mitochondrial metabolism

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The membrane was then incubated at room temperature in blocking solution for 1 hour, followed by incubation in blocking solution containing the appropriate dilution of either phospho-Jak2 or the primary antibody for growth hormone receptor, for 2 hours