Some individuals may have altered GLP-1 receptor function, which limits drug effectiveness
The coefficient of variation of LCMS 2 measurement approach 20%, which could limit analysis of smaller variation between our groups
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The choice for K = 10 was based on a combination of minimizing cross-validation errors for admixture analysis, as well as minimizing the Frobenius distance of each ADMIXTURE matrix K with the matrix outputted by Genetic Relationship and Fingerprinting
Circulating IGF-I deficiency and GH hypersecretion induce insulin resistance which is further augmented by insufficient suppression of hepatic glucose output
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