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387 Notably, the CKD-FIX study and the PERL trials demonstrated that allopurinol did not significantly slow the deterioration of estimated glomerular filtration rate (eGFR) in chronic kidney disease patients compared to placebo, over a span of 2 and 3 years, respectively
Future studies should employ stratified analyses or doseresponse curves to explore the influence of different GSH doses on prognosis, offering guidance for more precise clinical application
Most B12 in the UK is injected into muscle, but the fatty subcutaneous route is a recognised alternative
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