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This leads to fatigue, reduced calorie burn, and weight gain, often around the midsection

Constipation: Less commonly, constipation can occur as the digestive system adjusts to slower gastric emptying

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the compound 1 used in the patent is not easy to obtain (the synthesis steps are relatively more, the cost is higher) and has low purity (in the process of preparing the compound 1 from the compound 6 in the previous step, the N-succinimide is easily removed while the tert-butyl group is removed)

Dose adjustments should be made by the healthcare professional prescribing and monitoring your medication